GPC Journal Club

Generalist-Primary Care Journal Club

The GPC Journal Club is led by GPC residents and faculty and fellows from the Division of General Medicine on a monthly or bi-monthly basis to discuss current literature applicable to the practice of general medicine. Below is a list of the articles discussed. 


10/2020 Pharmacotherapy for Adults With Alcohol Use Disorders in Outpatient Settings. JAMA 2014
Screening for Unhealthy Drug Use. JAMA 2020

10/2020 Oak Street Health: A New Model of Primary Care. HBS 2017

9/2020 Disparities In Outcomes Among COVID-19 Patients In A Large Health Care System In California. Health Affairs 2020

9/2020 Telemedicine and Healthcare Disparities: A cohort study in a large healthcare system in New York City during COVID-19. Oxford University Press 2020

8/2020 Structural racism and health inequities in the USA: evidence and interventions. Lancet 2017
Race, Gender, and Partnership in the Patient-Physician Relationship. JAMA 1999
Physicians and Implicit Bias: How Doctors May Unwittingly Perpetuate Health Care Disparities. JGIM 2013
Access to transplantation for persons with intellectual disability: Strategies for nondiscrimination. AJT 2019 

6/2020 Hidden in Plain Sight — Reconsidering the Use of Race Correction in Clinical Algorithms. NEJM 2020
Association between health literacy and medication adherence in the treatment of hypertension among Hispanic patients. J. Racial and Ethnic Health Disparities 2019
Disparities in PAD especially in the American South: The Black American Amputation Epidemic. ProPublica
CDC report from 2019 on racial/ethnic disparities in maternal mortality and any further updates and research that have come from its publication last year.


3/2020 Milk and Health. NEJM 2020

1/2020 Alcohol Abstinence in Drinkers with Atrial Fibrillation. NEJM 2020

12/2019 Supplemental MRI Screening for Women with Extremely Dense Breast Tissue. NEJM 2019
Polypill for Cardiovascular Disease Prevention in an Underserved Population. NEJM 2019

9/2019 Dapagliflozin in Patients with Heart Failure and Reduced Ejection Fraction. NEJM 2019

7/2019 C-Reactive Protein Testing to Guide Antibiotic Prescribing for COPD Exacerbations. NEJM 2019

7/2019 Intensive Glucose Control in Patients with Type 2 Diabetes — 15-Year Follow-up. NEJM 2019

7/2019 Fracture Prevention with Zoledronate in Older Women with Osteopenia. NEJM 2018


4/2019 Effect of a Workplace Wellness Program on Employee Health and Economic Outcomes. A Randomized Clinical Trial. JAMA 2019

3/2019 Effect of a Behavioral Intervention Strategy on Sustained Change in Physical Activity and Sedentary Behavior in Patients With Type 2 Diabetes. The IDES_2 Randomized Clinical Trial. JAMA 2019

3/2019 Multitarget Stool DNA Testing for Colorectal-Cancer Screening. NEJM 2014

2/2019 Multivitamins in the Prevention of Cardiovascular Disease in Men. JAMA 2012

2/2019 Association of Clinical and Social Factors With Excess Hypertension Risk in Black Compared With White US Adults. JAMA 2018

1/19 Association Between Physician Burnout and Patient Safety, Professionalism, and Patient Satisfaction. A Systematic Review and Meta-analysis. JAMA 2018

1/19 A Cluster-Randomized Trial of Blood Pressure Reduction in Black Barbershops. NEJM 2018

12/18 Gait Speed and Survival in Older Adults. JAMA 2011

11/18 Effect of a Remotely Delivered Tailored Multicomponent Approach to Enhance Medication Taking for Patients With Hyperlipidemia, Hypertension, and Diabetes. JAMA 2018

10/18 Effect of Aspirin on Disability-free Survival in the Healthy Elderly. NEJM 2018
Effect of Aspirin on All-Cause Mortality in the Healthy Elderly. NEJM 2018

10/18 Effect of Intensive Blood-Pressure Treatment on Patient-Reported Outcomes. NEJM 2017

9/18 Spironolactone versus placebo, bisoprolol, and doxazosin to determine the optimal treatment for drug-resistant hypertension (PATHWAY-2): a randomised, double-blind, crossover trial. Lancet 2015

8/18 Association of Initiation of Basal Insulin Analogs vs Neutral Protamine Hagedorn Insulin With Hypoglycemia-Related Emergency Department Visits or Hospital Admissions and With Glycemic Control in Patients With Type 2 Diabetes. JAMA 2018

8/18 Clinicians' Perspectives on Providing Emergency-Only Hemodialysis to Undocumented Immigrants. Ann Intern Med. 2018

8/18 Assessment of the Safety of Discharging Select Patients Directly Home From the Intensive Care Unit. A Multicenter Population-Based Cohort Study. JAMA 2018

7/18 Evaluation of the Pooled Cohort Risk Equations for Cardiovascular Risk Prediction in a Multiethnic Cohort From the Women’s Health Initiative. JAMA 2018


5/18 Relationship between Clinic and Ambulatory Blood-Pressure Measurements and Mortality. NEJM April 19, 2018

4/18 Quadrupling Inhaled Glucocorticoid Dose to Abort Asthma Exacerbations. NEJM March 8, 2018

4/18 Effect of Opioid vs Nonopioid Medications on Pain-Related Function in Patients With Chronic Back Pain or Hip or Knee Osteoarthritis Pain The SPACE Randomized Clinical Trial. JAMA 2018

2/18 Comparison of Hospital Resource Use and Outcomes Among Hospitalists, Primary Care Physicians, and Other Generalists. JAMA 2017

12/17 Effect of a Primary Care Management Intervention on Mental Health–Related Quality of Life Among Survivors of Sepsis. A Randomized Clinical Trial. JAMA 2016

11/17 Prevention, Detection, Evaluation, and Management of High Blood Pressure in Adults JAMA 2017

10/17 Expansion of Treatment for Hepatitis C Virus Infection by Task Shifting to Community-Based Nonspecialist Providers: A Nonrandomized Clinical Trial

9/17 Effect of a Primary Care Management Intervention on Mental Health–Related Quality of Life Among Survivors of Sepsis

8/17 Structural racism and health inequities in the USA: evidence and interventions. Lancet 2017

8/17 Quarter-dose quadruple combination therapy for initial treatment of hypertension: placebo-controlled, crossover, randomised trial and systematic review. Lancet 2017

7/17 Effect of Insulin Degludec vs Insulin Glargine U100 on Hypoglycemia in Patients With Type 2 Diabetes. The SWITCH 2 Randomized Clinical Trial. JAMA 2016


9/2016 Association of Proton Pump Inhibitors With Risk of DementiaA Pharmacoepidemiological Claims Data Analysis JAMA 2016

7/2016 United States Health Care Reform Progress to Date and Next Steps by Barack Obama, JD NEJM

9/16 A Randomized Trial of Intensive versus Standard Blood-Pressure Control NEJM 11/15

1/17: "Appointment Availability after Increases in Medicaid Payments for Primary Care" NEJM 2016

2/17 N Engl J Med. 2016 Oct 27;375(17):1617-1627.

A Randomized Trial of Long-Term Oxygen for COPD with Moderate Desaturation.

Thorax. 2015 May;70(5):492-4. doi: 10.1136/thoraxjnl-2014-205720. Epub 2014 Dec 3.

Oxygen for relief of dyspnoea in people with chronic obstructive pulmonary disease who would not qualify for home oxygen: a systematic review and meta-analysis.

3/17: Reevaluation of Diagnosis in Adults With Physician-Diagnosed Asthma

Shawn D. Aaron, MD1; Katherine L. Vandemheen, MScN1; J. Mark FitzGerald, MD2; et al JAMA 2016

4/17 Early Performance of Accountable Care Organizations in Medicare NEJM 2016

6/17 The Oregon Experiment — Effects of Medicaid on Clinical Outcomes Katherine Baicker, Ph.D., Sarah L. Taubman, Sc.D., Heidi L. Allen, Ph.D., NEJM 201



7/25/14 Medicine and the Epidemic of Incarceration in the United States, NEJM, 2011

Release from Prison — A High Risk of Death for Former Inmates, NEJM, 2007

8/21/14 Housing as Healthcare, Public Roles of Physicians

9/5/14 Transforming Primary Care: From Past Practice To The Practice Of The Future. Health Affairs, 2010

10/31/14 Health diplomacy: a new approach to the Muslim world? Globalization and Health, 2014

11/14/14 From personal survival to public health: community leadership by men who have sex with men in the response to HIV. Lancet, 2012

12/17/14 Blocker Use and Clinical Outcomes in Stable Outpatients With and Without Coronary Artery Disease JAMA, 2010

1/21/15 Dying with Dignity in the Intensive Care Unit, NEJM, 2014

The world’s major religions’ points of view on end-of-life decisions in the intensive care unit. Intensive Care Medicine, 2007

2/20/15 Neighborhood Socioeconomic Disadvantage and 30-Day Rehospitalization, Annals, 2014

3/17/15 Finding the Right Words at the Right Time — High-Value Advance Care Planning, NEJM

Change in End-of-Life Care for Medicare Beneficiaries Site of Death, Place of Care, and Health Care Transitions in 2000, 2005, and 2009. JAMA 2013

4/20/15 ‘‘Oops! I forgot HIV’’: Resident physician self-audits and universal HIV screening” Journal of Infection and Public Health, 2015

9/6/13 The Oregon Experiment - Effects of Medicaid Expansion on Clinical Outcomes. NEJM, May 2013

12/12/13 Crossing Boundaries- Violation or Obligation? JAMA, Sept 2013

2/25/14 Joint National Commission HTN Guidelines and Commentary

3/8/2014 Twenty five year follow-up for breast cancer incidence and mortality of the Canadian National Breast Screening Study: randomised screening trial. BMJ, 2014

3/18/2014 Treatment of Blood Cholesterol to Reduce Atherosclerotic Cardiovascular Disease Risk in Adults: Synopsis of the 2013 American College of Cardiology/American Heart Association Cholesterol Guideline. Annals, 2014

7/20/12 High-Value, Cost-Conscious Health Care: Concepts for Clinicians to Evaluate the Benefits, Harms, and Costs of Medical Interventions , Annals

Appropriate Use of Screening and Diagnostic Tests to Foster High-Value, Cost-Conscious Care

8/17/12 Spencer et al. Effectiveness of a Community Health Worker Intervention Among African American and Latino Adults with Type 2 Diabetes: A Randomized Controlled Trial. AJPH, 2011

9/21/12 Heijnsdijk et al. Quality-of-Life Effects of Prostate-Specific Antigen Screening. NEJM, Aug 2012

Schroder et al. Prostate-Cancer Mortality at 11 Years of Follow-up. NEJM, Mar 2012

11/2/12 Rejeski et al. Lifestyle Change and Mobility in Obese Adults with Type 2 Diabetes. NEJM, 2012 Schauer et al. Bariatric Surgery versus Intensive Medical Therapy in Obese Patients with Diabetes. NEJM, April 2012

11/16/12 Sutton et al. Reduced Mortality with Hospital Pay for Performance in England. NEJM, Nov 2012

2/15/13 Sommers et al. Mortality and Access to Care among Adults after State Medicaid Expansions. NEJM, Sept 2011

3/22/13 Dhalla et al. Chlorthalidone Versus Hydrochlorothiazide for the Treatment ofHypertension in Older Adults. Annals of Internal Medicine, 2013

7/22/11 Boceprivir for Untreated Chronic HCV Genotype 1 Infection, Poordad F et al, NEJM, 2011

A New Era of Hepatitis C Therapy Begins, Jensen D, NEJM, 2011

8/26/11 Bisphosphonate Use and the Risk of Subtrochanteric or Femoral Shaft Fractures in Older Women. Park-Wyllie, L et al. JAMA, 2011

9/16/11 Racial and Ethnic Approaches to Community Health (REACH) Detroit Partnership: Improving Diabetes-Related Outcomes Among African American and Latino Adults. Two Feathers J., et al. American Journal of Public Health, 2005

11/18/11 Results of the Medicare Health Support Disease Management Pilot Program, NEJM, Nov 2011

12/16/11 Screening for Prostate Cancer: A Review of the Evidence for the U.S. Preventive Services Task Force, Annals of Internal Medicine, 2011

2/17/12 A Two-Year Randomized Trial of Obesity Treatment in Primary Care Practice, NEJM, Nov 2011

12/29/09 “A Lifeline for Primary Care” by Thomas Bodenheimer, M.D., Kevin Grumbach, MD, New England Journal of Medicine.

12/29/09 “Contribution of Primary Care to Health Systems and Health” by Barbara Starfield, Leiyu Shi, James Macinko. The Milbank Quarterly.

1/29/10 “Screening for Breast Cancer: An Update for the U.S. Preventive Services Task Force” by Heidi D. Nelson et al. Ann Intern Med.

1/29/10 “Effects of Mammography Screening Under Different Screening Schedules: Model Estimates of Potential Benefits and Harms.” Jeanne S. Mandelblatt, et al. Annals of Internal Medicine.

3/10/10 Thinking Outside the Pillbox — Medication Adherence as a Priority for Health Care Reform David M. Cutler, et al. New England Journal of Medicine.

8/11/10 “The Triple Aim: Care, Health, and Cost. The remaining barriers to integrated care are not technical; they are political.” by Donald M. Berwick, Thomas W. Nolan, and John Whittington. Health Affairs.

8/11/10 “The Cost Conundrum.” Gwande, A. The New Yorker, 2009

9/22/10 “The Burden of Blood Pressure-Related Disease A Neglected Priority for Global Health.” Vlado Perkovic, Rachel Huxley, Yangfeng Wu, Dorairaj Prabhakaran, Stephen MacMahon. Hypertension.

12/10/10 “Safety and efficacy of long-term statin treatment for cardiovascular events in patients with coronary heart disease and abnormal liver tests in the Greek Atorvastatin and Coronary Heart Disease Evaluation (GREACE) Study. Vasilios G Athyros, et al. Lancet.

12/28/10 “Long-term effect of aspirin on colorectal cancer incidence and mortality: 20-year follow-up of five randomised trials.” Peter M Rothwell, et al. Lancet.

2/7/11 Genomic Medicine, An Updated Primer. Feero, W. NEJM, 2010, 362:21. Genomics, Type 2 Diabetes, and Obesity. McCarthy, M. NEJM, 2010, 363:24.

3/28/11 Diagnostic Imaging for Low Back Pain: Advice for High Value Health Care from the American College of Physicians. Chou, R. Annals of Internal Medicine, 2011; 154:181-189.

4/22/11 Contextual Errors and Failures in Individualizing Patient Care. Weiner S, et al. Annals of Internal Medicine, 2010;153:69-75