Clinical Trials

  • BenfoTeam Trial: A new approach in early Alzheimers disease research, including Mild Cognitive Impairment and early dementia

    Principal Investigator:

    Jose A Luchsinger, MD, MPH
    The BenfoTeam clinical research trial is based on evidence from decades of research on the role of thiamine in Alzheimer's disease (AD). BenfoTeam scientists have found that thiamine (vitamin B1) does not enter the brains of people with early Alzheimer's disease despite having a sufficient supply of thiamine in their blood. Fortunately, there is also evidence that this problem with thiamine in the brain may be overcome by boosting the amount of thiamine in the blood far above usual levels. Benfotiamine, a lab-made version of thiamine, is the drug being tested in the BenfoTeam trial. BenfoTeam...

  • Lifestyle Patterns Study

    Principal Investigator:

    Marie-Pierre St-Onge, PhD
    The overall goal of this project is to assess the role of rest-activity patterns on glucose control, body composition, and well-being. We are currently looking for non-smoking men and women, age 25 years or older and with pre-diabetes (HbA1c 5.7-6.9%) to participate in this study. You must regularly sleep at least 6 hours/night and have variable sleep schedule (meaning going to bed and waking at different hours throughout the week). In addition, you must be willing to come to Columbia University Irving Medical Center for testing procedures. The screening process will take approximately 2...

  • Meal Timing Study (20-49 Yrs)

    Principal Investigator:

    Marie-Pierre St-Onge, PhD
    The overall goal of this project is to determine whether the timing of your meals influences health. We are currently looking for healthy, non-smoking, men and women to participate in this study. You must regularly sleep at least 7-9 hours/night and regularly eat close to wake time. In addition, you must be willing to come to Columbia University Irving Medical Center once a week for two 6-week periods and undergo laboratory testing for 2 consecutive days, twice in each period. Compensation up to $1,675 will be provided.

  • Nutrition Study

    Principal Investigator:

    Marie-Pierre St-Onge, PhD
    We are currently looking for healthy, nonsmoking adults ages 25-65yrs who are dissatisfied with their sleep to participate in a sleep study. Participants should find their sleep not refreshing but not taking external sleep aids. Participants must be willing to eat different foods for two periods of 4 days and undergo testing over a 24-hour period at the Columbia University Irving Medical Center. Compensation of up to $500 will be provided for completing all study measurements. For more information and to see if you may be eligible, please e-mail: dh3078@cumc.columbia.edu

  • The Yo-Yo Sleep Study

    Principal Investigator:

    Marie-Pierre St-Onge, PhD
    We are currently looking for healthy nonsmokers, ages 18-49yrs who are satisfied with their sleep to participate in a sleep study. Participants should typically sleep 7-9 hours/night without external sleep aids. Participants must be willing to change their sleep schedule for approximately 4 weeks. Compensation of up to $1000 will be provided for completing all study measurements. In addition, you must be willing to come to Columbia University Irving Medical Center for a baseline visit and once every other week for the study duration.

  • Ultra-Processed Food Effect on Weight Change

    Principal Investigator:

    Faris Zuraikat, PhD
    The purpose of this study is to assess energy balance during two different diet periods.