Yiyi Zhang, PhD, MHS

  • Assistant Professor of Medical Sciences (in Medicine) at the Columbia University Medical Center
Profile Headshot


Dr. Zhang's research focuses on understanding the determinants of cardiovascular health and identify strategies to reduce the burden of cardiovascular disease, particularly from a life course perspective. Dr. Zhang is the PI of three NIH/NHLBI R01 projects which aim to identify optimal strategies for blood pressure and lipid control in US young adults that are both cost-effective and improve health equity.

Academic Appointments

  • Assistant Professor of Medical Sciences (in Medicine) at the Columbia University Medical Center

Credentials & Experience

Education & Training

  • PhD, Epidemiology, John Hopkins University



  • 2023-2027
    NIH/NHLBI R01HL168379
    Zhang (PI)
  • 022-2027
    NIH/NHLBI R01HL159077
    Zhang (Site PI)
  • 2021-2026
    NIH/NHLBI R01HL155081
    Zhang (PI)
  • 2021-2026
    NIH/NHLBI R01HL158790
    Zhang (PI)

Selected Publications

  1. An J, Zhang Y, Zhou H, Zhou M, Safford MM, Muntner P, Moran AE, Reynolds K. Incidence of Atherosclerotic Cardiovascular Disease in Young Adults at Low Short-Term But High Long-Term Risk. J Am Coll Cardiol. 2023;81(7):623-32.
  2. Zhang Y, An J, Reynolds K, Safford MM, Muntner P and Moran AE. Trends of Elevated Low-Density Lipoprotein Cholesterol, Awareness, and Screening Among Young Adults in the US, 2003-2020. JAMA Cardiol. 2022;7:1079-1080.
  3. Zhang Y, Pletcher MJ, Vittinghoff E, Clemons AM, Jacobs DR, Jr., Allen NB, Alonso A, Bellows BK, Oelsner EC, Zeki Al Hazzouri A, Kazi DS, de Ferranti SD and Moran AE. Association Between Cumulative Low-Density Lipoprotein Cholesterol Exposure During Young Adulthood and Middle Age and Risk of Cardiovascular Events. JAMA Cardiol. 2021;6:1406-1413.
  4. Zhang Y, Schwartz JE, Jaeger BC, An J, Bellows BK, Clark D, 3rd, Langford AT, Kalinowski J, Ogedegbe O, Carr JJ, Terry JG, Min YI, Reynolds K, Shimbo D, Moran AE, Muntner P. Association Between Ambulatory Blood Pressure and Coronary Artery Calcification. Hypertension. 2021;77(6):1886-94.
  5. Zhang Y, Woo JG, Urbina EM, Jacobs DR, Jr., Moran AE and de Ferranti SD. Low-Density Lipoprotein Cholesterol Trajectories and Prevalence of High Low-Density Lipoprotein Cholesterol Consistent With Heterozygous Familial Hypercholesterolemia in US Children. JAMA Pediatr. 2021;175:1071-1074.
  6. Zhang Y, Vittinghoff E, Pletcher MJ, Allen NB, Zeki Al Hazzouri A, Yaffe K, Balte PP, Alonso A, Newman AB, Ives DG, Rana JS, Lloyd-Jones D, Vasan RS, Bibbins-Domingo K, Gooding HC, de Ferranti SD, Oelsner EC, Moran AE. Associations of Blood Pressure and Cholesterol Levels During Young Adulthood With Later Cardiovascular Events. J Am Coll Cardiol. 2019;74(3):330-41.