Eldad A. Hod, MD

Board Certifications: 
Blood Banking/Transfusion Medicine, Pathology-Anatomic/Pathology-Clinical
Accepting New Patients
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Overview

Areas of Expertise / Conditions Treated

Transfusion Medicine

Academic Appointments

  • Associate Professor of Pathology & Cell Biology

Administrative Titles

  • Associate Director, Automated Core Laboratories
  • Director, Center for Advanced Laboratory Medicine

Hospital Affiliations

  • NewYork-Presbyterian/Columbia

Gender

  • Male

Insurance Accepted

Aetna

  • EPO
  • HMO
  • Medicare Managed Care
  • NY Signature
  • NYP Employee Plan
  • POS
  • PPO
  • Signature Administrators
  • Student Health

Cigna

  • EPO
  • Great West
  • HMO
  • POS
  • PPO

Emblem/GHI

  • Medicare Managed Care
  • PPO

Emblem/HIP

  • ConnectiCare
  • EPO
  • Essential Plan
  • HMO
  • Medicaid Managed Care
  • Medicare Managed Care
  • POS
  • PPO
  • Select Care (Exchange)
  • Vytra

Empire Blue Cross Blue Shield

  • Blue Access (Exchange)
  • EPO
  • Gatekeeper (Exchange)
  • HMO
  • Medicare Managed Care
  • Pathway (Exchange)
  • POS
  • PPO

Local 1199

  • Local 1199

MagnaCare

  • MagnaCare

Multiplan

  • Multiplan

MVP Health Care

  • Child/Family Health Plus
  • Essential Plan
  • HMO
  • Medicaid Managed Care

Oxford Health Plans

  • Freedom
  • Liberty
  • Medicare Managed Care

UnitedHealthcare

  • Columbia University Employee Plan
  • Compass (Exchange)
  • HMO
  • Medicaid (Community Plan)
  • Medicare Managed Care
  • POS
  • PPO

*Please contact the provider’s office directly to verify that your particular insurance is accepted.

Credentials & Experience

Education & Training

  • Mount Sinai School of Medicine
  • Residency: NewYork-Presbyterian Hospital/Columbia University Medical Center
  • Fellowship: New York Blood Center

Board Certifications

  • Blood Banking/Transfusion Medicine
  • Pathology-Anatomic/Pathology-Clinical

Honors & Awards

1994                            Westinghouse Finalist

2004                            Arnold P. Gold Humanism in Medicine Honors Society

2005                            Alpha Omega Alpha (AOA)

2010                            Louis V. Gerstner, Jr., Scholar

2014                            Jean Julliard Prize 

2014                            National Blood Foundation (NBF) Scholar

2014                            Jack Latham Memorial Award for Innovative Research, National Blood Foundation (NBF)

Research

My current research program uses in vitro systems, mouse models, and human studies to investigate important problems relating to red blood cell transfusion and iron biology, particularly related to refrigerated storage, iron deficiency, hemolytic transfusion reactions, red blood cell senescence, and phagocytosis. 

Clinical Trials

Donor Iron Deficiency Study (DIDS) - ClinicalTrials.gov NCT02889133. A randomized trial to determine if red blood cells from donors with iron deficient erythropoiesis have decreased post-transfusion red blood cell recovery and whether iron repletion improves recovery.

Grants

TITLE: RECIPIENT EPIDEMIOLOGY AND DONOR EVALUATION STUDY IV - PEDIATRIC (REDS-IV-P) DOMESTIC HUB (Federal Gov)

Apr 1 2019 - Mar 31 2026

CLINICAL STUDY PROTOCOL FOR THE ESTABLISHMENT OF REFERENCE INTERVALS FOR ASSAY APPLICATIONS ON THE SYSMEX CS-2500 AND CS-5100 ANALYZERS (WAVE G) (P&S Industry Clinical Trial)

Oct 25 2018 - Oct 25 2023

ANALYTICAL AND CLINICAL PERFORMANCE TESTING PLAN (P&S Industry Clinical Trial)

Apr 12 2018 - Apr 12 2023

THE ESTABLISHMENT OF REFERENCE INTERVALS OF ASSAY APPLICATIONS ON SYSMEX CS-2500 AND CS-5100 ANALYZERS (WAVE E AND WAVE F) (P&S Industry Clinical Trial)

Mar 26 2018 - Mar 26 2023

ATELLICA UAS 800 ANALYZER CLINCAL TRIAL PROTOCL-EXTERNAL SITE TESTING (P&S Industry Clinical Trial)

Feb 21 2018 - Feb 21 2023

EXTERNAL VALIDATION OF THE HL (PART 1) AND MDA FEATURE IN THE SYSMEX AUTOMATED BLOOD COAGULATION ANALYZER CS-2500 AND CS-5100 (P&S Industry Clinical Trial)

Oct 31 2017 - Oct 31 2022

EXTERNAL PERFROMANCE STUDY FOR INNOVANCE FREE PS AG, V1.0,2016-11-23 (P&S Industry Clinical Trial)

Jun 22 2017 - Jun 22 2022

NEUROCOGNITIVE EFFECTS OF IRON DEFICIENCY IN BLOOD DONORS. (Federal Gov)

Dec 15 2017 - Nov 30 2021

EXTERNAL PERFORMANCE EVALUATION OF THE HL (PART1) AND MDA FEATURE IN THE SYSMEX AUTOMATED BLOOD COAGULATION ANALYZERS CS-2500 AND CS-5100 (P&S Industry Clinical Trial)

Jul 20 2015 - Jul 20 2021

RED BLOOD CELLS FROM IRON-DEFICIENT DONORS: RECOVERY AND STORAGE QUALITY (Federal Gov)

Aug 15 2016 - Apr 30 2021

HARMFUL EFFECTS OF TRANSFUSION-INDUCED IRON OVERLOAD (Federal Gov)

Jan 1 2019 - Dec 31 2020

THE SAFETY OF RED BLOOD CELL TRANSFUSIONS (Federal Gov)

Jul 1 2014 - Dec 31 2018

SUPPORT OF TESTING APTAMERIC SENSORS IN CLINICAL SAMPLES (Private)

Jan 1 2017 - May 31 2018

BIOMET BIOLOGICS PILOT PROJECT (Private)

Jul 15 2015 - Jul 14 2017

TRANSFUSION-RELATED IRON OVERLOAD AND POST-TRANSPLANTATION OUTCOMES IN A CHEMOTHERAPY-BASED MOUSE MODEL OF ALLOGENEIC STEM CELL TRANSPLANT. (Private)

Jul 1 2016 - Jun 30 2017

MECHANISMS UNDERLYING THE HARMFUL EFFECTS OF STORED RED BLOOD CELL TRANSFUSIONS (Federal Gov)

Jul 15 2010 - Apr 30 2015

RED CELL STORAGE DURATION STUDY (RECESS) (Federal Gov)

Apr 16 2013 - Dec 31 2013

EFFECT OF REPEAT BLOOD DONATION ON ATHEROSCLEROSIS AND CANCER RISK IN MURINE MODELS (Private)

Jul 1 2011 - Jun 30 2013

Selected Publications

1.  Hod EA, Zhang N, Sokol SA, Wojczyk BS, Francis RO, Ansaldi D, Francis KP, Della-Latta P, Whittier S, Sheth S, Hendrickson JE, Zimring JC, Brittenham GM, Spitalnik SL. Transfusion of red blood cells after prolonged storage produces harmful effects that are mediated by iron and inflammation. Blood. 2010;115: 4284-92.

2. Jang J, Hod EA, Spitalnik SL, Frenette P. CXCL1 and its receptor, CXCR2, mediate murine sickle cell vaso-occlusion during hemolytic transfusion reactions. J Clin Invest. 2011;121(4):1397-401. PMCID: PMC3069787.

3. Hod EA, Brittenham GM, Billote GB, Francis RO, Ginzburg YZ, Hendrickson JE, Jhang J, Schwartz J, Sharma S, Sheth S, Sireci A, Stephens HL, Stotler BA, Wojczyk BS, Zimring JC, Spitalnik SL. Transfusion of human volunteers with older, stored red blood cells produces extravascular hemolysis and circulating non-transferrin-bound iron. Blood. 2011;118(25):6675-82. PMID: 22021369. PMCID: PMC3242722.

4. Callan MB, Patel RT, Rux AH, Bandyopadhyay S, Sireci AN, O’Donnell PA, Ruane T, Sikora T, Marryott K, Sachais BS, Hod EA. Transfusion of 28 Day-Old Leukoreduced or Non-Leukoreduced Stored Red Blood Cells Induces an Inflammatory Response in Healthy Dogs. Vox Sang. 2013 Nov;105(4):319-327. PMID: 23763639. PMCID: PMC3797206.

5. Prestia K, Bandyopadhyay S, Slate AR, Francis RO, Francis KP, Spitalnik SL, Fidock DA, Brittenham GM, Hod EA. Transfusion of stored blood impairs host defenses against gram-negative pathogens in mice. Transfusion. 2014 Nov;54(11): 2842-51. PMID: 24840185. PMCID: PMC4229414.

6. Steiner ME, Ness PM, Assmann SF, Triulzi DJ, Sloan SR, Delaney M, Granger S, Bennett-Guerrero E, Blajchman MA, Scavo V, Carson JL, Levy JH, Whitman G, D’Andrea P, Pulkrabek S, Ortel TL, Bornikova L, Raife T, Puca KE, Kaufman RM, Nuttall GA, Young PP, Youssef S, Engelman R, Greilich PE, Miles R, Josephson CD, Bracey A, Cooke R, McCullough J, Hunsaker R, Uhl L, McFarland JG, Park Y, Cushing MM, Klodell CT, Karanam R, Roberts PR, Dyke C, Hod EA, Stowell CP. Effects of red cell storage duration in cardiac surgery patients. N Engl J Med. 2015; 372(15):1419-29. PMID: 25853746.

7. L'Acqua C, Bandyopadhyay S, Francis RO, McMahon DJ, Nellis M, Sheth S, Kernie SG, Brittenham GM, Spitalnik SL, Hod EA. Red blood cell transfusion is associated with increased hemolysis and an acute phase response in a subset of critically ill children. Am J Hematol. 2015; 90(10):915-20. PMID: 26183122.

8. de Swart L, Hendriks JC, van der Vorm LN, Cabantchik ZI, Evans PJ, Hod EA, Brittenham GM, Furman Y, Wojczyk B, Janssen MC, Porter JB, Mattijssen VE, Biemond BJ, MacKenzie MA, Origa R, Galanello R Deceased, Hider RC, Swinkels DW. Second International Round Robin for the Quantification of Serum Non-Transferrin-Bound Iron and Labile Plasma Iron in Patients with Iron-Overload Disorders. Haematologica. 2016 Jan;101(1):38-45. PMID: 26385212. PMCID: PMC4697890.

9. Yaghi S, Boehme AK, Hazan R, Hod EA, Canaan A, Andrews HF, Kamel H, Marshall RS, Elkind MS. Atrial Cardiopathy and Cryptogenic Stroke: A Cross-sectional Pilot Study. J Stroke Cerebrovasc Dis. 2016 Jan;25(1):110-4. PMID: 26476588 PMCID: PMC4695267.

10. Elkind MSV, Hills NK, Glaser CA, Lo WD, Amlie-Lefond C, Dlamini N, Kneen R, Hod EA, Wintermark M, deVeber GA, Fullerton HJ, and the VIPS Investigators*. Herpesvirus Infections and Childhood Arterial Ischemic Stroke: Results of the VIPS Study. Circulation. 2016 Feb 23;133(8):732-41. PMID: 26813104.

11. Gibb DR, Calabro S, Liu D, Tormey CA, Spitalnik SL, Zimring JC, Hendrickson JE, Hod EA*, Eisenbarth SC*. The Nlrp3 Inflammasome Does Not Regulate Alloimmunization to Transfused Red Blood Cells in Mice. EBioMedicine. 2016 9:77-86.

12. Fullerton HJ, deVeber GA, Hills NK, Dowling MM, Fox CK, Mackay MT, Kirton A, Yager JY, Bernard TJ, Hod EA, Wintermark M, Elkind MS; VIPS Investigators. Inflammatory Biomarkers in Childhood Arterial Ischemic Stroke: Correlates of Stroke Cause and Recurrence. Stroke. 2016 47:2221-8. PMID: 27491741

13. Barasch J, Hollmen M, Deng R, Hod EA, Rupert PB, Abergel RJ, Allred BE, Xu K, Darrah SF, Tekabe Y, Perlstein A, Wax R, Bruck E, Stauber J, Corbin KA, Buchen C, Slavkovich V, Graziano J, Spitalnik SL, Bao G, Strong RK, Qiu A. Disposal of iron by a mutant form of lipocalin 2. Nat Commun. 2016 Oct 31;7:12973.

14. Rapido F, Brittenham GM, Bandyopadhyay S, La Carpia F, L'Acqua C, McMahon DJ, Rebbaa A, Wojczyk BS, Netterwald J, Wang H, Schwartz J, Eisenberger A, Soffing M, Yeh R, Divgi C, Ginzburg YZ, Shaz BH, Sheth S, Francis RO, Spitalnik SL, Hod EA. Prolonged red cell storage before transfusion increases extravascular hemolysis. J Clin Invest. 2017 Jan 3; 127(1):375-382.